Flood Fatalities: April 2008 Monthly Total: 10 Vehicle Related: 6
| Day | State | County | Gender | Age | Circumstances |
| 1 | TN | Shelby | M | 56 | Tow truck operator attempting to save man who had driven into flood waters after falling asleep at the wheel. The tow truck driver was swept off the top of the car and perished. |
| 1 | MS | Tunica | M | 23 | Drowned when fell into flood waters attempting to secure family boat |
| 1 | MS | Tunica | M | 63 | Drowned when he fell into flood waters after leaving a bar |
| 2 | AR | Randolph | M | teen | Drowned when boat he was in capsized in flood waters |
| 3 | TN | Obion | M | 24 | Crowned when victim drove off roadway into flooded creek |
| 5 | KY | Crittenden | F | 2 | Mother drove into 8 feet of water over road at a creek crossing. Vehicle capsized and child swept away. |
| 10 | MO | Wright | M | 54 | Victim drove truck attempted to cross flooded bridge and swept away |
| 10 | MO | Shannon | M | 14 | Victim attempted to cross flooded creek with the aid of a cable across the creek. Lost his grip and swept away. |
| 11 | AR | Yell | M | 56 | Drove around barricade and drove approximately 1/8 mile when water was too deep and truck swept away. Highway had been closed and barricaded for more than 24 hours when fatalities occurred. |
| F | 55 |